The mixtape features guest appearances from Young Thug, Polo G, G Herbo, and Moneybagg Yo.

[4] On the originally planned release date, NLE Choppa was interviewed by HotNewHipHop and revealed that Young Thug and Moneybagg Yo will both appear on the project.

He commentated his opinion on it: Me vs. Me is, pretty much, a project concept I've been wanting to get out for a long time.

[7] The third single, "Jumpin", which features American rapper Polo G, was released on November 5, 2021.

[10] The sixth and final single, "Too Hot", which features American rapper Moneybagg Yo, was released on January 14, 2022.