The Medal "In Commemoration of the 250th Anniversary of Leningrad" was awarded to: workers, technicians and employees of industrial enterprises, transportation and urban development of Leningrad; to people working in science, technology, the arts, literature, education and health; to employees of state institutions, party, trade unions, Komsomol and other public organizations; who distinguished themselves in working in the reconstruction of the city and ensured the development of its own labour in industry, transportation, urban development, and in academic and cultural institutions; to soldiers and pensioners, to war or labour related invalids; to housewives who took an active part in the improvement of the city and in the work of schools and childcare facilities.

Award was conditional to having resided in the city of Leningrad or its suburbs for a minimum of 5 years.

On the obverse in relief, the Lenin Monument at the Finlyandsky Rail Terminal with the Neva River and Russian Admiralty in the background.

Below Lenin, the image of the hammer and sickle with a laurel branch at its left and unfolded banners at its right.

At the top, along the circumference of the medal, the inscription "In Commemoration of the 250th Anniversary of Leningrad" (Russian: «В память 250-летия Ленинграда».