[citation needed] He became Creative Management's vice president of the motion picture department in 1967, working with Steven Spielberg and Francis Ford Coppola, among others.

There he was part of the team responsible for making One Flew Over the Cuckoo's Nest, Rocky, and Annie Hall, which won Best Picture Oscars in 1975, 1976, and 1977 respectively.

United Artists made more notable films at the time including Apocalypse Now, Raging Bull, Network, The Black Stallion, and Coming Home.

[9] In 1978, Medavoy co-founded Orion Pictures which was a joint venture with Warner Brothers, and fellow United Artists executives Arthur Krim; Robert Benjamin; Eric Pleskow; and William Bernstein.

[10] While Medavory was at Orion, the company released notable and successful films including Platoon, Amadeus, RoboCop, Hannah and Her Sisters, The Terminator, Dances with Wolves, and The Silence of the Lambs.

[9] In 1990, Medavoy became the chairman of TriStar Pictures and oversaw the release of films such as Philadelphia, Terminator 2: Judgment Day, Sleepless in Seattle, Cliffhanger, The Fisher King, Legends of the Fall, and Hook.

[12] As its chairman and CEO, he co-produced such films as The People vs. Larry Flynt, The Mirror Has Two Faces, U Turn, Apt Pupil, The Thin Red Line, The 6th Day, Basic, All the King's Men, Zodiac, Pathfinder, and Miss Potter, among others.

Black Swan was directed by Darren Aronofsky and won numerous awards including the Oscar® and Golden Globe for Best Actress (Natalie Portman).

The feature was an adaptation of the novel The Cursed Piano, a love story set in Japanese-occupied China about persecuted Jews seeking refuge from occupied Europe.

For Kids (Community Outreach Assistance for Children's Heath, with Cedar Sinai Medical Center) and Irena Medavoy is the Executive Vice Chairman.

In 2009, Mike published American Idol After Iraq; Competing for Hearts and Minds in the Global Media Age, with co-author Nathan Gardels,[21] editor of the National Political Quarterly.