In 1958, the high school was refounded and moved into a new building, but then was added on to in 1970 to encompass the growing number of students being enrolled.

[5] In February 2018, a threat was made against the school by a student and was investigated by the Spokane County Sheriff's Office.

[8] In November 2021, a bombing threat against Medical Lake High School was exposed.

A building moratorium by the city of Medical Lake and a sluggish economy have also contributed.

[10] MLHS grew in the 1970s from 487 in 1970[11] to 650 in 1978,[12] but declined in the early 1980s to below 500 in 1983 and athletics dropped from the 'AA' Frontier League and returned to the 'A' NEA in 1984.