"Medicine Show" is a song by English band Big Audio Dynamite, released as both a 7" and 12" single from their debut studio album, This Is Big Audio Dynamite (1985).

Written by Mick Jones and Don Letts about a fictitious medicine show, and following the success of "E=MC2", "Medicine Show" was released as the third and final single from the album, peaking at No.

42 on Billboard's Modern Rock Tracks chart.

[1][2] It was their final top 40 single in the UK with the original line-up.

The music video for "Medicine Show", directed by Don Letts, featured two other former members of the Clash, Joe Strummer and Paul Simonon as police officers as well as Neneh Cherry and Andi Oliver of band Rip Rig and Panic, and John Lydon of the Sex Pistols and Public Image Ltd. Sampled liberally throughout this song are sound bites from four motion pictures, three of them Spaghetti Westerns.