They built a manor house on the ruins of the ancient castle and for generations maintained in their family seat a cultural centre with a valuable library and historical collections.

It includes a single page containing a Polish version of Psalm 50, known as the Karta medycka, from the early 15th century, discovered in Medyka in 1832 by historian and collector, Konstanty Świdziński [pl] (1793-1855).

[3] The Polish 23rd Observation Escadrille was stationed in Medyka during the joint German-Soviet invasion of Poland, which started World War II in September 1939.

The British society portrait painter and illustrator, Aniela Pawlikowska, was married to the last proprietor of Medyka, Michał Gwalbert Pawlikowski [pl] (1887-1970), a bibliophile, writer, and publisher who lived, worked and raised their family there, before being routed from their home by invading forces in World War II.

Medyka is one of the main road border crossings between Poland and Ukraine, along with a major railway line running through the village, connecting both countries.