Montefusco has previously played for the Chicago Red Stars in the Women's Premier Soccer League, for NWSL teams Washington Spirit, Boston Breakers, Reign FC and Houston Dash, as well as the Newcastle Jets in the Australian W-League.

Raised in Naperville, Illinois, Montefusco attended Neuqua Valley High School where she led the soccer to team to a 24–0 record and first place national ranking.

[1] Montefusco played club soccer for Windy City Pride from 1998 to 2011 and was a member of the regional Olympic Development Program (ODP) for five years.

[1] Prior to leaving for college, Montefusco played briefly for the Chicago Red Stars in the Women's Premier Soccer League in 2011.

[3] Chicago topped the Midwest Conference North Division and reached the Championship final, eventually losing to Orange County Waves in extra-time 2–1.

[1] UCLA retained the Pac-12 conference title and reached the 2014 NCAA College Cup quarterfinals before losing 2–1 to Virginia Cavaliers, the only game the Bruins gave up more than one goal in 2014.

[9] Montefusco began her professional career in 2011 with the Chicago Red Stars, then playing in the second-tier Women's Premier Soccer League.

[20] In her first season with Reign, Montefusco started 21 games and scored once as the team finished third, dropping from second with a final day defeat to Portland Thorns FC before losing in the playoff semifinals to the same opponent a week later.

[22] On February 3, 2020, Houston Dash acquired Montefusco in a trade with Reign FC along with Shea Groom and a second-round pick in the 2022 NWSL Draft in exchange for Sofia Huerta and Amber Brooks.

[24] She played every minute of the 2021 NWSL Challenge Cup and made a further 21 appearances during the regular season as Houston finished in seventh-place, missing the playoffs by one point.

[25] On January 28, 2022, Orlando Pride acquired Montefusco in a trade with Houston along with $30,000 in allocation money and a third-round pick in the 2023 NWSL Draft in exchange for Marisa Viggiano.