A researcher and Anti-Defamation League fellow with a focus on right-wing political extremism online,[1] her work has been described as operating as an intermediary between non-profits like the Southern Poverty Law Center and militant groups on the far-left.

[3][2] Squire's research focuses on how online extremism is mediated by social media networks, including Telegram,[4] Facebook,[3] and other platforms.

[5] She has also explored how the younger generation of far right extremists, including Nick Fuentes and Patrick Casey, use video livestreaming and gaming platforms to earn money.

A study in November 2020 showed that a handful of leaders of the global white nationalist movement are raising significant sums of money.

Squire first engaged in activism at age 15, when she joined her school environmental club to protest pollution at an industrial cattle farm.

In 2022, Squire was named a Belfer Fellow by the Anti-Defamation League for her work to "collect, analyze, and visualize quantitative data from social media platforms to understand the impact of various types and levels of deplatforming and demonetization on far-right individuals and groups.