[1] Megarine lies in a large area of palm plantations on an oasis network that extends from Sidi Slimane past Touggourt through to Balidat Ameur.

Beyond the oases is the arid and barren landscape of the Sahara, featuring areas of sand dunes (ergs) and flat rocky plains (regs).

Megarine is connected to the N3 national highway a short 2.5 kilometres (1.6 mi) long local road.

From the intersection, the town is connected to Biskra to the north, and Touggourt 9 kilometres (5.6 mi) to the south.

The train line from Biskra to Touggourt also runs near the town at the junction of the local road with the N3.