[6] She came close to winning her first professional event at the GolfUppsala Open on the LET Access Series in August 2021, missing to join a playoff with Kajsa Arwefjäll and Sofie Bringner by one stroke to finish third.

[8] Örtengren was runner-up at the French International Lady Juniors Amateur Championship in November 2021 and rounded off the season by winning the AJGA's 44th annual Rolex Tournament of Champions at PGA National Resort and Spa in Palm Beach Gardens, Florida, with a six-stroke victory over Alexa Pano.

[9][10] In May 2022, Örtengren, still an amateur, captured her first win in a professional tournament, the Swedish PGA Championship Trelleborg on the LET Access Series after a playoff with Zhen Bontan.

[11] In August 2022, Örtengren won the Espirito Santo Trophy at Le Golf National in France together with Ingrid Lindblad and Louise Rydqvist, where she also recorded the lowest individual score, tied with Helen Briem and Rose Zhang.

[14] In April 2024, she won the European Nations Cup – Copa Sotogrande with the Swedish team by 17 strokes ahead of England in second, and she was runner-up for the individual title behind only her compatriot Elin Pudas Remler.