2017—2018 After promotion to the Ethiopian Premier League, the club officials sacked manager Getachew Dawit who helped the team earn spot in the top division.

After the club's first season in the top division, Mekelle 70 Enderta parted ways with head coach Yohannes Sahle.

July 7, 2019 (date of the last match of the league) was a historic day for the Red Lioness as Fasil City drop two points against Shire Endaselassie F.C.

in the last match of the league and Mekelle 70 Enderta winning over Dire Dawa City with the help of Amanuel Gebremichael and Osei Mawuli goals.

The team is named after the city it was founded in, Mekelle 70 Enderta (the capital of the northern Tigray Region of Ethiopia).

As of 12 January 2020 Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.