The Mel Fisher Maritime Museum is located at 200 Greene Street, Key West, Florida.

The museum contains an extensive collection of artifacts from 17th century shipwrecks, such as the Henrietta Marie, Nuestra Señora de Atocha and Santa Margarita.

A rotating gallery exists on the second floor of the museum and is currently displaying an exhibit or artifacts belonging to Cuban Rafters, Balseros, who arrive to Key West in hand-crafted vessels.

Terrestrial archaeological sites include The African Cemetery of Key West, located on Higgs Beach.

Some artifacts, depending on type and density, can take anywhere from weeks to years for full conservation before they are placed on display in the museum.