Melvin Anthony Hoderlein (June 24, 1923 – May 21, 2001) was an American utility infielder in Major League Baseball who played from 1951 through 1954 for the Boston Red Sox (1951) and Washington Senators (1952–54).

A steady infielder with good instincts, Hoderlein is better known as a player who was part of seven major league franchises but only played for two of them.

After being discharged, he was part of several transactions before debuting in the majors in August 1951 with the Red Sox, while hitting .357 (5-for-14) in nine games.

Hoderlein gave three years of good services for Washington, coming out of the bench as a defensive replacement and for pinch-hitting duties.

In a four-season career, Hoderlein was a .252 hitter (74-for-294) with 22 runs and 24 RBI in 118 games, including 10 doubles, three triples, two stolen bases, and a .327 on-base percentage.