Melaleuca amydra is a plant in the myrtle family, Myrtaceae and is endemic to the south-west of Western Australia.

The flowering season is spring and is followed by fruit which are woody capsules, 3–3.5 mm (0.12–0.14 in) long in irregular clusters along the stems.

[2][3]Melaleuca amydra was first formally described in 1999 by Lyndley Craven and Brendan Lepschi in Australian Systematic Botany from a specimen collected near Eneabba.

[4][5] The specific epithet (amydra) is from the ancient Greek amydros meaning "indistinct" or "unclear", referring to the minor differences between this species, M. ryeae and M.

[2] This melaleuca occurs in and between the Arrowsmith River, Dandaragan and Moora districts[2] in the Avon Wheatbelt, Geraldton Sandplains and Swan Coastal Plain biogeographic regions.