Melaleuca diosmifolia is a plant in the myrtle family, Myrtaceae and is endemic to the south-west of Western Australia.

[2][3] Melaleuca diosmifolia was first formally described in 1807 by Henry Cranke Andrews in The Botanist's Repository for New, and Rare Plants.

[2] Melaleuca diosmifolia occurs near the coast of Western Australia between Cape Riche and Albany[3] in the Esperance Plains, Jarrah Forest and Warren biogeographic regions.

[7] This species has also become naturalised in the Otway Ranges[3] district of Victoria, where it is considered an environmental weed.

[8][9] Melaleuca diosmifolia is listed as "not threatened" by the Government of Western Australia Department of Parks and Wildlife.