Melaleuca thapsina is a plant in the myrtle family, Myrtaceae and is endemic to the south-west of Western Australia.

Flowering occurs mainly in spring and is followed by fruit which are woody capsules, 2.0–2.5 mm (0.08–0.1 in) long, packed tightly together in spherical or oblong clusters.

[2][3] Melaleuca thapsina was first formally described in 1999 by Lyndley Craven in Australian Systematic Botany from a specimen collected 110 km (70 mi) north-east of Lake King on the track to Norseman.

[4][5] The specific epithet (thapsina) is derived from the Ancient Greek word thapsinos meaning "yellow"[6] referring to the colour of the flowers.

[3] Melaleuca thapsina is listed as "not threatened" by the Government of Western Australia Department of Parks and Wildlife.