The Darwin's toad's natural habitats are temperate shrubland, intermittent freshwater marshes, and sandy shores.

This species can be found on the coast of the Río de la Plata and the Atlantic Ocean, from Santiago Vázquez (Montevideo) to Praia da Alvorada ( Rio Grande do Sul ).

When being held by hand, the specimens usually remain motionless with their belly up, displaying their red and yellow coloration.

[2] The Darwin's toad is considered a Critically Endangered (CR) species in Uruguay and globally Vulnerable (VU)[4] due to habitat loss from urbanization of the areas where it lives.

[2] Some models predict a total disappearance of the climatic conditions where this species is distributed, which could cause its extinction by mid-century, due to its reproductive behavior being dependent on rainfall and temperatures in the warm months.