[1] The team at Supergiant Games felt that the little information available for Melinoë was compelling, wanting to explore her story and familial connections, as well as "expand [their] vision of the underworld.

[5] Fellow Siliconera writer Brent Koepp agreed, finding himself relating to the rivalry between Melinoë and Nemesis, saying that it had his "blood boiling at first."

[7] Rolling Stone writers Christopher Cruz and Nikki McCann Ramirez contrasted her character from Zagreus, describing him as a jock while Melinoë was "much more studious, relentlessly disciplined, and overflowing with her own charm.

[11] ZME Science writer Andrei Mihai discussed the similarities and differences between Melinoë in Hades II and the mythological figure.

He noted certain liberties taken with the depiction, arguing that whether the mythological figure was an individual goddess is disputed, as well as whether she was the daughter of Zeus or Hades.