The Mellette House is a historic home and museum located at 421 Fifth Avenue Northwest in Watertown, South Dakota.

When the house was condemned in 1943, a group purchased the property and formed the Mellette Memorial Association to restore and preserve it.

The house was added to the National Register of Historic Places in 1976.

[2] There are pictures of the Mellette family in the house along with original furniture and household items.

This article about a property in South Dakota on the National Register of Historic Places is a stub.