Blister beetles are hypermetamorphic, going through several larval stages, the first of which is typically a mobile triungulin.
The adults sometimes feed on flowers and leaves of plants of such diverse families as the Amaranthaceae, Asteraceae, Fabaceae, and Solanaceae.
[1] Cantharidin, a poisonous chemical that causes blistering of the skin, is secreted as a defensive agent.
Cantharidin is the principal irritant in "Spanish fly", a folk medicine prepared from dried beetles in the family Meloidae.
The oldest fossil of the group is a larva (triangulin) found phoretic on a schizopterid bug from the mid Cretaceous Burmese amber, dated to around 99 million years ago.