[6] Though she briefly quit playing in her teen years, after Creager moved to the east coast to attend Philadelphia College of Art and Parsons School of Design, she was convinced by friends to take it up again.
[10] In 1991, Creager founded alternative cello ensemble Rasputina by writing a manifesto and placing a want-ad in the Village Voice stating "electric cellists wanted".
Rasputina performed regularly at NYC venues such as CBGB's Gallery, Brownie's and Fez before being signed to Columbia Records in 1996, for whom they subsequently made two albums.
Inspirations include the Triangle Shirtwaist Factory fire of 1911, Howard Hughes, Rose Kennedy, victims of Josef Mengele, Emily Dickinson, Pitcairn Island, and Columbia County, New York.
[16] Creager played cello with Nirvana on the European leg of their In Utero world tour in 1994, including the band's final show in Munich.
The Compilation, a webpage containing poems, songs and art in memory of "those we've lost to suicide or overdose", included contributions from Melissa Auf der Maur and John Cafiero.
Creager has been a frequent collaborator of Voltaire, playing cello on his albums Riding a Black Unicorn... (2011), Raised by Bats (2014) and Heart Shaped Wound (2017).