The suburb was named after early South Australian aviator, Charles James Melrose.

[3] The most common countries of birth were Australia (75.7%), the United Kingdom (3.1%), China (2.4%), Nepal (2.1%) and India (2.1%).

[3] The age distribution of Melrose Park residents is slightly older than that of the Australian population as a whole.

[3][4] Melrose Park is part of Overton Ward in the local government area of the City of Mitcham.

[7] The suburb is represented in the South Australian House of Assembly by Nadia Clancy[8] and federally by Louise Miller-Frost.