The Men's United States Squash Open 2012 was the men's edition of the 2012 United States Open (squash), which is a PSA World Series event Gold (Prize money: $115,000).

The event took place at the Daskalakis Athletic Center in Philadelphia, Pennsylvania in the United States from 6 October to 12 October.

Ramy Ashour won his first US Open trophy, beating Grégory Gaultier in the final.

For 2012, the prize purse was $115,000.

The prize money and points breakdown is as follows:[1] [2]