The Vario proved a popular base chassis for trucks, minibuses and mini-coaches.

When new regulations required disabled access, a model with a wheelchair lift was made available.

From September 2000, Vario 618D/818D models were equipped with a 4.2-liter turbo diesel engine with intercooler and direct injection with an output of 136 or 150 hp and torque of 520 or 580 Nm, respectively.

With the introduction of the Euro 4 emission standards, the Vario began to be equipped with OM904LA series BlueTec4 turbocharged and intercooled engine with working volume of 4250 cm3 and a power of 129, 156 or 177 hp.

[5] All models had a suspension on parabolic leaf springs, all ventilated disc brakes and power steering.