Meserich Synagogue, Meserich Shul or Meseritz Shul, also known as Edes Israel Anshei Mesrich, Edath Lei'Isroel Ansche Meseritz or Adas Yisroel Anshe Mezeritz ("Community of Israel, People of Mezertiz"), is an Orthodox Jewish synagogue located at 415 East 6th Street, in the East Village of Manhattan, New York City, New York, United States.

The congregation was established in 1888, comprising immigrants from Międzyrzec Podlaski, a city in Biała Podlaska County, Lublin Voivodeship, Poland, known as a center of Jewish learning.

The unusually narrow building has balconies which extend almost to the middle of the sanctuary, and through the intervening space, broad rays of light from two overhead skylights seem to focus on the Ark and on a large stained glass panel above it.

"[2] After experiencing dwindling attendance and facing financial difficulties due to the ongoing maintenance of the synagogue building,[8] the congregation began negotiations with Joshua Kushner, part of the family that owns the New York Observer newspaper.

[13] The synagogue temporarily relocated during the development and reopened in March 2017[14] with a ceiling put at balcony level above the restored sanctuary to separate it from the luxury apartments that were built.