Several authors have connected Meskhetians or Meskhians to Mushki tribe or Moschoi (Μόσχοι) in Greek sources, who were an Iron Age people of Anatolia.

Meskhian tribes came to the fore, gradually moving northeast and forming their settlements in the very heart of Kartli.

Mtskheta, the ancient capital of Iberia (literarily means "town of Meskhs") was one such settlement, deriving its name from the ethnonym "Meskhians".

Rustaveli is the author of The Knight in the Panther's Skin, which is considered to be a Georgian national epic poem.

Thereafter, the kingdom of Georgia declined and eventually disintegrated under hegemony of various regional powers, including the Mongols, Timurids, Black and White Sheeps.