Mesopotam (Albanian definite form: Mesopotami; Greek: Μεσοπόταμος - Mesopotamos) is a village and a former commune in Vlorë County, southern Albania.

[2] The population at the 2011 census was 2,786,[3] Besides the village Mesopotam from which it takes its name and which functions as well as an administrative center, the administrative unit consists of 14 other villages: Ardhasovë, Bistricë, Brajlat, Dhrovjan, Fitore, Kardhikaq, Kostar, Kranë, Krongj, Livinë, Muzinë, Pecë, Sirakat, and Velahovë.

[4] The People's Republic of Albania (1945-1991) established cultural rights in special minority zones for ethnic Greeks in all 14 villages of Mesopotam.

[5][6] According to a fieldwork of 1995 the majority of the villages, including Mesopotam itself, are inhabited solely by the Greek community, while Muzinë and Pecë, by the Albanian Orthodox.

[7] The Mesopotam village is known for its 13th century Orthodox Church dedicated to St. Nicholas, declared "Protected Monument" from the government.