[1] The stated aim of mesotherapy is to provide the skin with essential nutrients, hydration, and other beneficial compounds to rejuvenate and revitalize its appearance.
[2] Pressurized mesotherapy is a needle-free method that uses an accelerated jet of air to insert the ingredients into the skin tissue.
[4] In the United States, deoxycholic acid, under the brand name Kybella, is approved by the Food and Drug Administration for reducing moderate-to-severe fat below the chin.
There is no conclusive research proof that any chemical compounds work to target adipose (fat cells) specifically.
[citation needed] Physicians have expressed concern over the efficacy of mesotherapy, arguing that the treatment hasn't been studied enough to make a determination.
[7] Rod Rohrich, M.D., chairman of the Department of Plastic Surgery at the University of Texas Southwestern Medical Center is quoted as saying: "There is simply no data, no science and no information, to my knowledge, that mesotherapy works."
Robin Ashinoff, speaking for the American Academy of Dermatology, wrote "A simple injection is giving people false hope.
[11] Following undesirable effects observed on several patients of a French practitioner, an official ratification was published in France in April 2011 to ban mesotherapy as a method for removing fat deposits.