[7] Early records of education in Metamora date back to 1836, when students attended classes taught in a log house by Betty Page.

Built at a cost of $8000 by Soloman E. Egbert, the two-story brick building featured 4 rooms, a grammar department being on the lower floor and a high school being on the second.

Most recently, profound population growth in both Metamora and neighboring Germantown Hills saw a significant expansion of MTHS in 2000.

It is bordered to the south by residential housing, to the west by a student parking lot, and to the east by McBride and Shoff, Inc. and Illinois Route 89.

The school's central portion, housing a library along with most of its classrooms and administrative offices, forms a two-story "H" with both levels following a similar layout.

The building's east portion sits at a level between the first and second floors, resembling a split-level design, and houses metal, wood, and automotive shops.

For the 2009–10 school year, MTHS failed to make Adequate Yearly Progress (AYP) on the Prairie State Achievement Examination (PSAE), comprising the ACT and WorkKeys examination, the assessment tool used in Illinois to fulfill the No Child Left Behind Act.

[3] Metamora Township High School competes in the Mid-Illini Conference, in which it is the reigning All-Sports Champion (2008–2009).

[14] MTHS sponsors both men's and women's teams in basketball, cross-country, golf, soccer, tennis, and track & field.