Methanosphaera is a genus of microbes within the family Methanobacteriaceae.

[1] It was distinguished from other genera within Methanobacteriaceae in 1985 on the basis of the oligonucleotide sequence of its 16S RNA.

[2] Like other archaea within Methanobacteriaceae, those of Methanosphaera are methanogens, but while most use formate to reduce carbon dioxide, those of Methanosphaera use hydrogen to reduce methanol to methane.

[3] This Euryarchaeota-related article is a stub.

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