The Hualapai Mexican vole (M. m. hualapaiensis) was formerly recognized as a subspecies and was a protected taxon under the United States Endangered Species Act until 2017.

Several other populations of the vole were previously named subspecies but are no longer recognized as distinct.

The Mexican vole mainly feeds on grasses and the roots of shrubs and trees.

(Beacham, 2000) In several studies, the Mexican vole was baited using two plant products, barley and oatmeal.

Separate populations which appeared to have different morphologies were sometimes named subspecies, such as Microtus mexicanus mogollonensis, M. m. hualpaiensis, and M. m. navaho.