It operates between El Rosario in the municipality of Azcapotzalco, in northern Mexico City, and Villa de Aragón in Gustavo A. Madero, in the eastern limits of the city with the municipality of Ecatepec de Morelos in the State of Mexico, Mexico.

Line 6 has a total of 37 stations and a length of 20 kilometers (12.4 mi), which runs from northwestern to eastern Mexico City.

[1] Construction of Line 6 started on August 6, 2014 and it was inaugurated on January 21, 2016 by Miguel Ángel Mancera, Head of Government of the Federal District from 2012 to 2018.

[2][3] The line has three itineraries:[4] Villa de Aragón to El Rosario Villa de Aragón to Instituto Politécnico Nacional Deportivo 18 de Marzo to El Rosario Line 6 services the Azcapotzalco and Gustavo A. Madero municipalities.

Corredor Antenas-Rosario, SA de CV (CARSA) is the sole operator of Line 6.