The Mexican Olympic Committee (Spanish: Comité Olímpico Mexicano) sent the nation's largest delegation to the Games since 1972, with a total of 124 athletes, 80 men and 44 women, competing across 26 sports.

[2] Mexico left Rio de Janeiro with five medals (three silver and two bronze), failing to win a single gold for the first time since the 2004 Summer Olympics in Athens.

[3][4] Among the medalists were race walker María Guadalupe González, semi-pro boxer Misael Rodríguez (men's middleweight), and modern pentathlete Ismael Hernández, who became the first ever Mexican to ascend the Olympic podium in his signature sport.

[5] Diver Germán Sánchez picked up his first individual medal at the Games with a silver in the men's platform, following a runner-up effort with his synchronized diving partner Iván García from London 2012.

[3] Taekwondo fighter María Espinoza made history as the first Mexican female to complete a full set of medals in three different Games, adding a silver to her Olympic career haul in the women's +67 kg.

[8] For individual-based sports, Mexico made its Olympic debut in mountain biking and golf (new to the 2016 Games), as well as its return to men's beach volleyball and tennis after 16 years.

Seven of the nation's Olympic medalists from London 2012 returned, including diving tandem Iván García and Germán Sánchez (men's synchronized platform), as well as their female counterparts Paola Espinosa and Alejandra Orozco (women's synchronized platform); archer and three-time Olympian Aída Román, taekwondo fighter María Espinoza, and football team captain Oribe Peralta, who helped the Mexicans score two goals for a shocking gold-medal victory over Brazil in the men's tournament final.

Note that reserves in fencing, field hockey, football, and handball are not counted as athletes: Mexican archers qualified for the women's events after having secured a top eight finish in the team recurve at the 2015 World Archery Championships in Copenhagen, Denmark.

[18] Joselito Velázquez, Lindolfo Delgado, and Juan Pablo Romero secured additional places on the Mexican roster at the 2016 APB and WSB Olympic Qualifier in Vargas, Venezuela.

[24] Mexico has entered one dressage rider into the Olympic equestrian competition by virtue of a top national finish from Central & South America at the 2015 Pan American Games in Toronto, Canada.

[28] Meanwhile, Julián Ayala, Alejandra Terán, and Nataly Michel rounded out the Mexican roster by virtue of a top two finish at the Pan American Zonal Qualifier in San José, Costa Rica.

Ismael Hernandéz and Tamara Vega secured a selection each in the men's and women's event respectively after obtaining one of the five Olympic slots from the Pan American Games.

Marcos Madrid and three-time Olympian Yadira Silva secured their Olympic spots in the men's and women's singles, respectively, by virtue of their top six finish at the 2016 Latin American Qualification Tournament in Santiago, Chile.

Due to the withdrawal of several tennis players from the Games, Santiago González and Miguel Ángel Reyes-Varela received a spare ITF Olympic place to compete in the men's doubles.

[59] Head coach: Jorge Azair Mexican weightlifters have qualified three women's quota places for the Rio Olympics based on their combined team standing by points at the 2014 and 2015 IWF World Championships.