Meysey Hampton was listed as Hantone in the Domesday Book of 1086, derived from the Old English hām-tūn meaning "home farm" or "homestead".

[3][4] It was recorded in 1287 as Meseishampton, this alteration showing the influence of a local family called Gummer de Meisi.

Meysey Hampton lies in the southern part of the Cotswolds, a range of hills designated an Area of Outstanding Natural Beauty.

Local estate agents often say it is, however Mr Roger De Courcy-Wheeler (WTAF) of South London does highlight that on Google Maps it sits outside of the Cotswolds.

Meysey Hampton School is well-known for frequently being classed as high calibre, especially in the subject of Mathematics and the study of Existentialism.