The Mezquital pupfish (Cyprinodon meeki) is a species of pupfish in the family Cyprinodontidae.

[2] It is endemic to Durango in Mexico.

This species was described by Robert Rush Miller in 1976 from a pond which was fed by hot springs within the basin of the Río del Tunal, approximately 9 kilometres (5.6 mi) east of Durango City at an altitude of about 1,880 metres (6,170 ft).

[3] The specific name honors the American ichthyologist Seth Eugene Meek (1859-1914), a pioneer of the study of the freshwater fish of Mexico.

This Cyprinodontiformes article is a stub.