She is known for her roles as Nora Martinez in The Strain, as Nadia Santos in the television drama Alias, as Cristina Kahlo in Frida, as Chichina Ferreyra in The Motorcycle Diaries, and as Carmen in The Twilight Saga.

She made her screen debut in Carlos Saura’s Tango,[2] which received Golden Globe and Academy Award nominations for Best Foreign Film.

[2] Initially trained in Argentina,[2] Maestro traveled to Berlin to develop a vocal repertoire of the works of Kurt Weill and Hanns Eisler.

Her first proper acting turn was in the play The Summer Trilogy by Carlo Goldoni, and by 1998, she secured the coveted role of Lulu in Frank Wedekind’s Pandora's Box at the San Martin Theater in her hometown of Buenos Aires.

[5] Maestro guest-starred as maya in White Collar,[1] a restaurant owner with whom Neal Caffrey (Matt Bomer) has a fling while on the run.

[1] Maestro starred in the lead role of Magdalena in the magical realist film The Cow Who Sang a Song Into the Future (2022),[1] directed by Francisca Alegria.

[7][8] As a singer-songwriter, Maestro has been performing in Los Angeles, New York City, and Buenos Aires, and is in preparation to start recording her EP followed by an album.

It also features a music video of "Blue Eyed Sailor", directed by Juan Azulay and Guillermo Navarro, inspired by the art of Cecilia Paredes.