She has a brother named Rafael "Rafa", who is a cinematographer, and two sisters, Milagros, who works as a yoga instructor, and Ximena "Xime", who is also a model.

While attending university, Argañaraz sent polaroids to the Buenos Aires agency LO and they called her for a meeting.

[13] Argañaraz began her career in 2012, walking for Christopher Kane and appearing in the Spanish and Italian editions of Glamour and Elle respectively.

[20] In advertising campaigns, she has modeled for Michael Kors, Versace, Louis Vuitton, Tom Ford, Calvin Klein, Yves Saint Laurent, Prada, Miu Miu, Chanel, Mango, Alexander McQueen, H&M, and Givenchy.

[21][22][23] On the runway, she has walked for designers including Prada, Miu Miu, Lacoste, Michael Kors, Valentino,[24] Fendi,[25] Alexander Wang, Dries Van Noten, Altuzarra, Jason Wu, Stella McCartney, Hugo Boss, Tom Ford, Chanel, Dior and Louis Vuitton.

[26][27][28] She has frequently been compared to supermodel Gia Carangi, who Argañaraz considers a beauty icon.