Miccosukee is a small unincorporated community and census-designated place (CDP) in northeastern Leon County, Florida, [United States.

[citation needed] It was mapped by the British in 1778 and originally called Mikasuki with 60 homes, 28 families, and a town square.

At the time he invaded Spanish Florida in 1818, during the First Seminole War, "Andrew Jackson and his men were stunned by the sheer size of the Miccosukee town.

After the Civil War, the area reverted to farms and by 1887, the Florida Central Railroad served Miccosukee.

The Great Depression (1929-1935) destroyed Leon County's agriculture[citation needed] and the railroad pulled out in the mid-1940s.