The following week he reached his first ATP World Tour final at the PBZ Zagreb Indoors, which he lost to Marin Čilić 4–6, 7–6(5), 3–6.

At the Dubai Tennis Championships in February, he defeated Sergiy Stakhovsky and Nikolay Davydenko to reach the third round, where he lost to Marcos Baghdatis, 6–7(5), 1–6.

At his first clay court tournament of the year in Monte-Carlo, he beat Evgeny Korolev and Juan Mónaco en route to a third-round showdown against Rafael Nadal, which he lost, 0–6, 1–6.

Two weeks later he defeated Tommy Robredo at the ATP World Tour Masters 1000 in Cincinnati, before losing to Richard Gasquet in two sets.

Berrer beat Guillermo García López, Pablo Cuevas, and Marcos Baghdatis en route to the semifinal in Vienna, where he lost to Austrian lucky loser Andreas Haider-Maurer.

He won his first Grand Slam match at the 2011 French Open against 26th seed Milos Raonic, before beating Arnaud Clément in the second round.