After his mother's death, his father married his second cousin, Lady Sarah Wilfreda Palmer, daughter of Earl Selborne and they lived at Douglas House, Petersham.

In 1865 he was elected to the House of Commons for Herefordshire, a seat he held until 1885, and then represented Ross between 1886 and 1900.

In 1903 he was raised to the peerage as Baron Biddulph, of Ledbury in the County of Hereford.

They had two sons and three daughters, including:[3] After her death in 1872 he married, secondly, Lady Elizabeth Philippa (née Yorke) Adeane, widow of Henry John Adeane MP for Cambridgeshire, in 1877.

Lord Biddulph died in April 1923, aged 89, and was succeeded in the barony by his eldest son from his first marriage, John.