[1] Before being drafted into the OHL, DiPietro played with the Sun County Panthers Minor Midget AAA team.

[4] In his sophomore year, DiPietro helped guide the Spitfires to a Memorial Cup victory, posting a .932 save percentage during Windsor's championship win.

[14] He made his NHL debut on February 11 in a 7–2 loss to the San Jose Sharks, stopping 17 of 24 shots.

[15] By making his debut, DiPietro became the second youngest Canucks goaltender in franchise history, only being surpassed by Troy Gamble.

[17] On March 18, 2019, DiPietro and teammate Cedrick Andree were announced as the co-winners of the Dave Pinkney Trophy for allowing the fewest goals against in the league.

On January 23, he would return to the NHL by starting against the St. Louis Blues in a 3–1 loss after goaltender Spencer Martin was also placed on the COVID-19 protocol, stopping 14 of 17 shots.

Before making his season debut, DiPietro was traded by the Canucks to the Boston Bruins, along with prospect Jonathan Myrenberg, in exchange for Jack Studnicka on October 27, 2022.

[23] On January 2, Canada was eliminated from the World Juniors tournament in a heartbreaking 2–1 overtime loss in the quarterfinals to Team Finland.

[24] DiPietro was named to Team Canada for the 2021 IIHF World Championship, whom with he had won a gold medal,[25] and the 2022 Spengler Cup.