His dissertation, and subsequent research program, focused on the evolution, ecology, and genetics of flour beetles of the genus Tribolium.
Thus, explaining and predicting many genetic and evolutionary phenomena in nature require understanding non-additive causal effects.
[4] In effect, Wade has found extensive empirical support, in the laboratory and in the field, for Sewall Wright's Shifting balance theory.
Wade's results, in concert with work by David Sloan Wilson, helped rekindle interest in group selection in the biological community.
Wade and his collaborators are increasingly employing rich genomics data and turning to other model systems, such as social insects.