A technically gifted player, Krohn-Dehli started his professional career in the Netherlands, but would make his breakthrough for native childhood club, Brøndby IF, where he amassed 26 goals in 122 Danish Superliga appearances.

This earned him a move to Celta in Spain, where he remained for the rest of his career, also representing Sevilla and Deportivo La Coruña.

[5][6] On 28 April 2016, he dislocated his left kneecap shortly after being subbed on in the first UEFA Europa League semi-final at Arena Lviv against Shakhtar Donetsk, much to the dismay of both teammates and opponents.

[7][8] He had knee surgery performed the following day at Clínica Sagrado Corazón de Sevilla after having flown back home with the rest of the squad.

[9] Later that day, following the surgery, Sevilla FC released a statement on the club's website, revealing that he would miss seven to eight months of action, depending on his rehabilitation.

[10] Almost six months later to the day, on 27 October, Sevilla released footage of a recovering Krohn-Dehli running on one of the club's training grounds.

[14] On 10 July 2020, a year after leaving Deportivo, Krohn-Dehli announced through his agent that he had officially retired from professional football and would pursuit a career as a pundit.