Spensieri ran for the Ontario legislature in the 1975 provincial election but lost to New Democratic Party candidate Odoardo Di Santo in Downsview by sixty-eight votes.
In late 1984, he was forced to issue an apology after sending out a newsletter which portrayed the New Democratic Party as "a group of socialists committed to the destruction of the separate school system and the murder of unborn children".
[3] After this, he wrote a number of letters to Toronto newspapers describing prominent Italian-Canadian figures in the Liberal Party as cultural misfits.
[4] In 1999, the socially conservative Family Coalition Party announced that Spensieri would be its candidate in York Centre for the 1999 provincial election.
[6] Spensieri retired from public life and promoted activities and fundraising in the areas of mental health and bipolar disorders.