He won his first regional championship—the European Union super-lightweight title—on 26 December 2006, defeating Giorgio Marinelli via unanimous decision (UD).

One defence of the title was made a month later, on 30 January 2007, when di Rocco travelled to Finland and scored a UD over Juho Tolppola.

On 21 September 2007, di Rocco lost his title to veteran and fellow Italian Giuseppe Lauri, who stopped him in seven rounds.

[1] Di Rocco's career highlight came on 8 June 2013, when he defeated Lenny Daws via UD to win the vacant European super-lightweight title.

On 28 May 2016, di Rocco travelled to Scotland to face former two-weight world champion Ricky Burns, with the vacant WBA super-lightweight title on the line.