Caruso-Cabrera challenged incumbent representative Alexandria Ocasio-Cortez in the 2020 Democratic primary for New York's 14th congressional district, which covers portions of the Bronx and Queens.

[5] She attended Wellesley College ('91) in Massachusetts, paying her tuition in part with the help of a National Merit Scholarship and her earnings from her first summer job as a waitress at Pizza Hut.

[6][7] Prior to graduation, she was elected editor of the college newspaper, and starting in 1991 she worked as a stringer for The New York Times, reporting for the education section.

In it, she called for the elimination of both Social Security and Medicare, which she characterized as "pyramid schemes", and expressed numerous other conservative positions.

[27] In addition, she proposed creating personal savings accounts saying they would lead people to work longer, and converting Medicare into a corporate-type 401(k) plan.

In 2020, Caruso-Cabrera tweeted, "I support Medicare and social security-its important to take care fo [sic] the most vulnerable.

[30] Caruso-Cabrera filed official paperwork on February 10, 2020, challenging freshman Representative Alexandria Ocasio-Cortez in the Democratic primary for New York's 14th congressional district, which covers portions of the Bronx and Queens.

[31][32][33][34][35] Caruso-Cabrera was endorsed by what Politico called the "traditionally conservative" United States Chamber of Commerce, a business lobbying group that generally backs Republicans.

[41] Caruso-Cabrera ran in the general election on the ticket of the Serve America Movement, a party with 349 registered members in New York.