[2] Rempel was acclaimed as the Conservative Party of Canada candidate in Calgary Centre-North on December 17, 2010, in anticipation of a by-election to replace Prentice.

She received positive media coverage in late 2011 for her strong performance during Question Period, and was seen as a rising star within the Conservative caucus.

[2] Rempel Garner played a role in the multi-partisan effort to create Sable Island National Park Reserve.

[13] The 2013 Hill Times Annual Most Valuable Politician & All Politics Poll awarded Rempel 2nd place in the "Best Up-and-comer MP" category behind Justin Trudeau.

In May 2020, Rempel Garner sponsored Parliamentary Petition E-2574, which aims to reverse the federal government's executive order that banned 1500 "assault style" weapons.

[5] In this role, Rempel Garner aimed to improve the delivery and efficiency of the department's services by focusing its attention on commercializing technology in emerging sectors such as green energy.

[20] To this end, she oversaw a series of investments that aimed to "accelerate technology development and performance validation, as well as the commercialization of key instruments associated with the underground storage of carbon dioxide (CO2).

[33] To this end, in May 2020, Rempel Garner launched the Conservative Party's ‘Connect Canada’ consultation initiative for action on rural internet access.

The initiative delivered a report outlining policy proposals that would aim for all Canadians to have access to affordable and reliable internet by the year 2021.

[34] In June 2020, Rempel Garner passed a motion with support from other opposition parties to have the Standing Committee on Industry, Science and Technology study the effects of foreign takeovers and the Investment Canada Act.

[37][38] In 2022, Rempel Garner wrote an article in favour of proportional representation during the debate on the 2022 Canadian federal electoral redistribution.

[41] The Sprawl criticized her response, arguing that it is part of a pattern whereby Rempel Garner "mimics the worst of American politics and attacks the media’s credibility" and opined that "her anti-media rants veered into full-on conspiracy theory.

[46] Rempel Garner won a court case against a Toronto area man who threatened her with violence over social media.

"[47] The Toronto Star revealed that "it only took Rempel about five minutes to block his Twitter account after he turned to social media to critique her stance on immigration.