Between 1999 and 2008, the Coliseum was home to the Wayne State University Warriors ice hockey team.

Between early 1999 and mid-2000, the Michigan State Fairgrounds Coliseum was the site of three Extreme Championship Wrestling house shows.

In 2006 the Royal Oak-Shrine Catholic High School Knights ice hockey team began playing at the State Fairgrounds Coliseum.

The Motor City Mechanics of the United Hockey League, which had suspended operations in 2006, planned to resume in 2008 and play at the Coliseum.

In 2020, the state fairgrounds were sold to Amazon; the company plans to convert the site into a $400 million distribution center.