[9][11][20] Still using the ring name Alexis Laree, she began making television appearances for OVW on January 29, 2004, and competed in several tag team matches throughout the year.

James later became the number one contender for the WWE Women's Championship on December 12, by defeating Victoria in a match to determine who would face Stratus at New Year's Revolution.

[citation needed] On the April 14, 2008, episode of Raw, held in London, England, James defeated Beth Phoenix to win her fourth Women's Championship.

[73] Throughout the Summer, Mickie successfully defended the title against Gail Kim and Beth Phoenix on episodes of Raw,[74][75] and against Alicia Fox at the Hell in a Cell pay-per-view on October 4.

[79] On the October 30 episode of SmackDown, a controversial angle began that saw WWE Women's Champion Michelle McCool and Layla, collectively known as LayCool, bully James.

[80] On the December 4 episode of SmackDown, James became the number one contender for McCool's Women's Championship by defeating Beth Phoenix and Natalya in a triple threat match.

[82][83] On the January 22 edition of Smackdown, another controversial segment in the feud took place when Laycool beatdown James, force-fed her a pig shaped cake and dumped a bowl of punch on her head, leaving her sobbing and defeated in the ring.

On the February 26 episode of SmackDown, McCool used her rematch clause to face James for the Women's Championship, with Guerrero acting as special guest referee.

[86] This set up a 10-Diva tag team match at WrestleMania XXVI, in which James made an unsuccessful in-ring return after Vickie pinned Kelly.

James' final match in WWE aired on the April 23 episode of SmackDown where she teamed with former long-time rival Beth Phoenix against LayCool in a losing effort when she was pinned by Layla.

[90] Sporadic appearances (2013) In November 2013, James served as guest trainer at the WWE Performance Center in Orlando, Florida, for a week, training NXT's female wrestlers.

[101] On September 21, James made an appearance at the Wrestling Spectacular 2 all-female event in Edison, New Jersey, alongside many former WWE and TNA female wrestlers, such as Angelina Love, Katarina Waters, Rosita and Brooke Adams.

Two months after giving birth to her child, James returned to in-ring competition at Queens Of Combat 3 on November 30, where she defeated Tessa Blanchard after turning heel during the match and resorting to villainous tactics.

[114] On September 2, 2016, James made her debut for Chikara, when she entered the 2016 King of Trios tournament as part of Team Original Divas Revolution, alongside Jazz and Victoria.

[133] On April 17, James defeated Madison Rayne in a steel cage match, which lasted less than a minute, to win the TNA Knockouts Championship for the first time.

[138] On June 18, James made her debut for TNA's Mexican partner Lucha Libre AAA Worldwide (AAA) at Triplemanía XIX, where she teamed with Angelina Love, Sexy Star and Velvet Sky to defeat Cynthia Moreno, Faby Apache, Lolita and Mari Apache in an eight-woman tag team match.

On the January 5, 2012, episode of Impact Wrestling, James and Traci Brooks failed to capture the TNA Knockouts Tag Team Championship from Kim and Rayne.

[155] On the January 26 episode of Impact Wrestling, James and Velvet Sky were defeated by Tara in a three-way number one contender's match for the Knockouts Championship.

[156] On the April 5 episode of Impact Wrestling, James was defeated by Sky in a six-way number one contenders match, also involving Angelina Love, Madison Rayne, Tara, and Winter.

[158] On the June 21 episode of Impact Wrestling, James was chosen over Sky as the next challenger for the Knockouts Championship, but failed to recapture the title from Ms.

[160] On the August 2 episode of Impact Wrestling, James unsuccessfully competed in a four-way number one contenders match involving Gail Kim, Tara and the eventual winner Madison Rayne.

[164] On January 13, 2013, at the Genesis pay-per-view, James competed in a five-woman gauntlet match to determine the number one contender to the Knockout Championship, but was eliminated by Gail Kim.

[177][178] James made a surprise return to TNA as a fan favorite, after a year and a half absence from the company, on January 30, 2015, during the tapings of Impact Wrestling in Glasgow, Scotland.

[180] On the June 3 episode of Impact Wrestling, James declined an offer by Storm to join The Revolution, which resulted in him intentionally shoving her onto a train track in the storyline, which sparked controversy.

[181] James made her return on the July 1 episode of Impact Wrestling, confronting Storm and challenging him to an intergender tag team match.

[192] She competed in her first match in nearly seven years in a WWE main roster ring on January 29, 2017, at the Royal Rumble pay–per–view, teaming with Bliss and Natalya against Lynch, Naomi, and Nikki Bella in a losing effort.

[232][233][234][235][236] On June 23, James announced on an Instagram video that she will be returning to the ring and delivers an open challenge to anyone to wrestle her at the NWA 73rd Anniversary Show.

[245][246] At Turning Point, after successfully retained the title against Mercedes Martinez, James was attacked by Purrazzo, who announced that she would invoke her rematch clause at Hard To Kill.

[272] James, along with Ken Anderson, represented WWE at the 2008 Republican National Convention, in an effort to persuade fans to register to vote in the 2008 Presidential election.

[294][295] James made a special appearance on Redemption Song which is hosted by Chris Jericho along with Candice Michelle, Maryse, and Eve Torres.