[12] In May 2004, a tournament was held to crown the first NWA Midwest/IWA Mid-South Women's Championship, during which Mickie advanced to the semi-finals before being defeated by Mercedes Martinez.

[13][unreliable source] Mickie won the NWA Midwest/IWA Mid-South Women's Championship on June 11, 2005, defeating MsChif and Allison Danger in a three-way match.

Ian Rotten, however, still recognized Mickie as the IWA Mid-South Women's Champion, leading to the titles splitting into two separate entities.

As such, Knuckles became the IWA Mid-South Women's Champion, keeping the title for five months before losing it to her first ever opponent Hailey Hatred, on 18 November 2005.

Knuckles would win the title back at an IWA East Coast event in February 2006, and held on to it until July 2007 before losing it to Chuck Taylor.

Less than a month later, Mickie won back her title by defeating Taylor in a Falls Count Anywhere match to regain the Women's Championship for a third time.

Before receiving a rematch for the IWA Women's Championship, Knuckles broke her right femur on July 6, 2008, after performing a diving crossbody off a platform onto Del Rey.

After defeating Tiffany in the first round and Hailey Hatred in the second, Mickie lost out in the finals to returning champion Mariko Yoshida.

She appeared on the June 5 edition of Impact!, coming to The Beautiful People's aid by attacking Gail Kim, ODB, and Roxxi.

[22] Two weeks later, Tracy caught Isabella listening to Boondox, the rapper who sings 2 Tuff Tony's entrance music.

Smothers was part of an eight-woman gauntlet match for the at OVW's Saturday Night Special on April 15, but was unsuccessful in winning the title.

[31] On October 11, Knuckles was unsuccessful in reclaiming the Women's Championship during a three-way match against Lady JoJo and Taeler Hendrix.

On December 10, Knuckles and Jessie Belle Smothers' OVW profiles were removed from the website, signalling their departure from the company.

After giving birth to her son and marrying her husband, fellow wrestler Justin Turner (also known as Jacob Black), Mickie Knuckles made her return to wrestling in May 2016.

Following this, Knuckles returned to Independent Wrestling Association Mid-South for the first time in four years, where she defeated Heidi Lovelace, Jordynne Grace, Randi West and Thunderkitty in a five-way match on December 6.

[33] After defeating Nick Esteban in an intergender Falls Count Anywhere Match on March 28, 2015, Knuckles announced she would be quitting wrestling for a little while a few weeks later on April 7 while also revealing that she was once again pregnant.

2021 Would be a calendar year for Knuckles as she had notable matches with the likes of AKIRA, Kennedi Copeland, Charlie Kruel and Randi West.

She won Slave To The Deathmatch 14 in September 2023 [42] Knuckles had a Very Notable Match With Lufisto at ICW No Holds Barred Volume 44 in March 2023.

[46] 1The IWA Mid-South Tag Team Championship was held jointly between Knuckles, Abercrombie and Moore under the Freebird Rule.